■ Experience
'82. 3 - '86. 2 Seoul National University, B.S. in Chemistry
'86. 3 - '88. 2 Seoul National University, M.S. in Chemistry
'89. 9 - '95. 6 Harvard University, Ph.D. in Chemistry
'95. 6 - '98. 8 University of Pennsylvania, Research Associate
'98. 8 - present Professor in Chemistry at Pusan National University
■ Research Interests
The relationships of Protein structure, function and dynamics
Reaction dynamics in condensed phase
Single molecule spectroscopy and its application to imaging
Development and application of new time-resolved spectroscopy
■ Selected Publications
1. “Probing Lipid Vesicles by Bimolecular Association and Dissociation Trajectories of Single Molecules.” Gao, Feng; Mei, Erwen; Lim, Manho; Hochstrasser, Robin M. Journal of the American Chemical Society (2006), 128(14), 4814-4822.
2. “Effects of Solvent Viscosity on Ligand Interconversion Dynamics in the Primary Docking Site of Heme Proteins.” Kim, Seongheun; Heo, Jeonghee; Lim, Manho. Journal of the American Chemical Society (2006), 128(9), 2810-2811.
3. “Protein Conformation-Induced Modulation of Ligand Binding Kinetics: A Femtosecond Mid-IR Study of Nitric Oxide Binding Trajectories in Myoglobin.” Kim, Seongheun; Lim, Manho. Journal of the American Chemical Society (2005), 127(25), 8908-8909.
4. “Ultrafast time-resolved IR studies of protein-ligand interactions.” Lim, Manho; Anfinrud, Philip A. Methods in Molecular Biology (2005), 305(Protein-Ligand Interactions), 243-259.
5. “Picosecond Dynamics of Ligand Interconversion in the Primary Docking Site of Heme Proteins.” Kim, Seongheun; Lim, Manho. Journal of the American Chemical Society (2005), 127(16), 5786-5787.
6. “Direct observations of ligand rebinding trajectories in myoglobin by femtosecond mid-IR spectroscopy.” Kim, Seongheun; Lim, Manho. Springer Series in Chemical Physics (2005), 79(Ultrafast Phenomena XIV), 625-627.
7. “Dynamics of geminate recombination of NO with myoglobin in aqueous solution probed by femtosecond mid-IR spectroscopy.” Kim, Seongheun; Jin, Geunyeong; Lim, Manho. Journal of Physical Chemistry B (2004), 108(52), 20366-20375.